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Composition Analysis Of Hyaluronic Acid

Qufu Focuschem Trading Co.,Ltd | Updated: Sep 09, 2017

     Hyaluronic acid (Hyaluronicacid, HA), also known as hyaluronic acid, is a acidic sticky polysaccharide, the 1934 American Columbia University ophthalmology Professor Meyer first from the bovine eye vitreous separation of the substance. Hyaluronic acid with its unique molecular structure and physical and chemical properties in the body to display a variety of important physiological functions, such as lubrication joints, regulate the permeability of vascular wall, regulate protein, water electrolyte diffusion and operation, promote wound healing and so on.Hyaluronic Acid
     It is particularly important that hyaluronic acid has a special water conservation effect, and is the best moisturizing substance found in nature, known as the ideal Natural moisturizing factor (Naturalmoisturizingfactor, NMF, for example: 2% of pure hyaluronic acid aqueous solution can hold 98% moisture firmly. Hyaluronic acid is a multifunctional matrix, HA is widely distributed in all parts of human body. The skin also contains a lot of hyaluronic acid. Human skin maturation and aging process also with hyaluronic acid content and metabolism changes, it can improve skin nutrition metabolism, make skin soft, smooth, wrinkle, increase elasticity, prevent aging, in the moisturizing at the same time is a good transdermal absorption promoter.Hyaluronic Acid
     In conjunction with other nutrients, it can be a better effect in promoting nutrient uptake. Sodium hyaluronate is an important component of extracellular matrix, which has the functions of adhesion and can protect the cornea. Because of its water retention, can prevent corneal dryness. adding fibrin Binder (FN) to the corneal epithelial cell matrix has a role in promoting adhesion. Thus, the injury of the conjunctival epithelium has protective effect. The Rabbit corneal epithelial injury model was tested by pharmacology.Hyaluronic Acid
     For iodine vapor and N-heptane-induced corneal epithelial exfoliation, with more than 0.1% of the concentration of this product can cause damage to 22h or 24h of the wound significantly reduced. For the corneal epithelial exfoliation caused by n-g alcohol, the reduction of wound after 24h was dose-dependent, and the content of this product was more than 0.05%. The operation of severe corneal epithelium stripping (damage to the basement membrane), the product of more than 0.1% concentrations can also be stripped 24h below the wound significantly reduced.Hyaluronic Acid
    For the corneal epithelial injury caused by vitamin A deficiency in rats, there was no significant difference between the 0.3% concentration and the matrix agent, but the staining fraction of the starvation group was significantly longer than that of the normal rearing group. The role of corneal epithelial cells in the tissue culture of rabbit cornea was added to the product 0.5mg/ml above, can obviously promote the extension of corneal epithelium. This effect was not seen in the same concentration of chondroitin sodium, sodium sulfate and sodium sulfate.Hyaluronic Acid