Academic Center

Home > Academic Center > Content

The Properties And Effects Of Chondroitin Sulfate

Qufu Focuschem Trading Co.,Ltd | Updated: Aug 25, 2017

    Chondroitin sulfate (CS) is a kind of sugar-amine oligosaccharide, which is covalent-linked to form protein-oligosaccharide on the protein. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues, the sugar chain consists of alternating glucose glyoxylic acid and N-acetyl galactose (also known as N-acetyl amino galactose), which is connected to the serine residues of the core protein through a sugar-like link region.Chondroitin Sulfate
    Chondroitin sulfate is present in all living organisms, from nematodes to humans, and plays many important physiological functions. Although the main chain structure of polysaccharides is not complex, it is highly heterogeneous in terms of the degree of sulfated, sulfuric acid and the distribution of two kinds of difference to the chain of the isomeric sugars. The fine structure of chondroitin sulfate determines the specificity of function and interaction with various protein molecules.Chondroitin Sulfate
    Firstly, the study of the types and contents of acidic polysaccharide in different tissues was introduced, and the presence of CS, hyaluronic acid and mucin in connective tissue was identified. Chemical properties, CS in acidic, alkaline and enzymatic hydrolysis of unsaturated sugar, including low molecular CS and CS of oligosaccharides or disaccharide are related to β-elimination reaction. The degree of degradation of CS in acidic, alkaline and neutral conditions is indicated by ultraviolet absorbance at 232nm, the greater the UV absorbance value indicates, the greater the degree of degradation is, and the stability of CS under different conditions is reflected.Chondroitin Sulfate
    Physical properties, CS is a kind of acidic polysaccharide material extracted from animal tissues, which is white or off-white powder; The aqueous solution of this product is viscous and does not condense. This product in water soluble, insoluble in ethanol, acetone, and ether and other organic solvents, its salts to heat more stable, heat up to 80 ℃ also not be destroyed. Chondroitin sulfate aqueous solution, in the event of higher temperature or acid is unstable, mainly the deacetylation or degradation of monosaccharides or small molecular weight of polysaccharides.Chondroitin Sulfate
    Product function: Provide cushion function, mitigate the impact and friction of action, can absorb water into protein polysaccharide molecule, thicken the cartilage, and increase the amount of synovial fluid in the joint. One of the important functions of chondroitin is to serve as a conduit for conveying vital oxygen and nutrients to the joints, helping to remove waste from the joints while excluding carbon dioxide and waste. Because the articular cartilage is not supplied with blood, all oxygenation, nourishment, and lubrication are derived from the synovial fluid. Chondroitin Sulfate
   Chondroitin sulfate has protective effect on corneal collagen fibers, which can promote the growth of fiber in the matrix, enhance permeability and improve blood circulation. Accelerate the metabolism, promote the absorption of osmotic fluid and the elimination of inflammation; its poly anion has strong water retention, can improve the moisture metabolism of cornea tissue, have strong affinity to cornea, can form a layer of breathable membrane in the cornea surface, improve the symptom of dry eye. By promoting the formation of matrix, the structure of cell migration is beneficial to the migration of corneal epithelial cells, thus promoting the healing of corneal trauma, the absorption of exudate and the elimination of inflammation.Chondroitin Sulfate
   Through high technology processing, can treat nerve headache, trigeminal neuralgia, coronary heart disease, angina pectoris, myocardial hypoxia, cardio-cerebrovascular disease, joint pain, atherosclerosis and hepatitis, including CS also has anticoagulant and antithrombotic effect, can also be used for streptomycin-induced hearing impairment and liver dysfunction of adjuvant treatment and high blood lipid adjuvant treatment. can be used as additives in food, with the strengthening of human body constitution and anti-bacteria, beauty, anti-aging and other functions. Improve hearing and dry skin. The body can inhibit the absorption of lipid and glucose in the small intestine to achieve weight loss.Chondroitin Sulfate